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Yes, it is absolutely safe for a breastfeeding mom to take antacids as directed.
The calcium and magnesium in antacids like Maalox and Tums are absorbed into your bloodstream, but they won't have a significant effect on your breast milk.
If over-the-counter antacids aren't strong enough to control your heartburn, there are prescription medications that are also safe for breastfeeding moms. Ask your pediatrician to look up the most recent information on prescription medications for reflux and choose the one that is most likely to relieve your symptoms and be safe for your baby.
Learn more about the safety of commonly used medications during breastfeeding.