Amniocentesis is most commonly used for the evaluation of prospective mothers with advanced maternal age in terms of chromosomal abnormality of your baby and for the definitive diagnosis in cases where a triple test or double test or quadruple test is detected. Amniocentesis (AS) is the name given to the amniotic fluid in the uterus and from where the baby is swimming in the uterus with a needle entered through the abdominal skin of the expectant mother and taking the fluid from here. After an ultrasound evaluation is performed again, the needle is removed and the procedure is terminated. It is administered one of the first two months of pregnancy. The amniotic fluid material is delivered to the laboratory at room temperature. The presence of chromosomal abnormality (such as Down syndrome) in one of the close relatives is one of the reasons for amnionsetesis. The quadruple test is measured by looking at four different values from the blood taken from the expectant mother, and the baby with the syndrome is checked. The clear and sterile fluid that the baby swims through during pregnancy is called amniotic fluid. This fluid allows the baby to move freely in the womb while protecting against external shocks and infections. It also protects the fetus from heat in summer and cold in winter by staying constant at 37 degrees. The amount of amniotic fluid increases with increasing baby weight. The amount of liquid, which is 20 ml in the seventh week of gestation, reaches 1 liter with peak between the 30th and 32nd weeks. Then it decreases slightly until 38 weeks and remains constant until birth as 800 ml. Resting after amniocentesis is necessary to protect the person and the baby from possible side effects. Physical activity should be reduced as much as possible within the first 24 hours following amniocentesis, and bed rest should be performed if possible. There should be no sexual contact for 3 days after amniocentesis. Following amniocentesis, high fever, severe abdominal pain, persistent cramps, bleeding in vagina or fluid discharge should be urgently applied to a health institution. the risk of giving birth is also increasing. An example of this is; Down syndrome. E.g; While a 25-year-old woman has a 1 / 1,348 chance of having a child with Down Syndrome, this is 1/900 at 30 and 1/381 at 35. The genetic structure of human is determined by 46 chromosomes in cell nucleus. These chromosomes are called chromosomal anomalies. Depending on chromosomal anomalies, intelligence symptoms, internal organs, hand-foot anomalies, growth retardation, clinical symptoms such as children with syndrome develop. NST, fetal distress (distress in the baby) and the presence of fetal distress In this case (such as decreased baby movements) as a first-line test. Some doctors perform NST only in risky situations, while some doctors routinely perform NST examination at each examination from a certain week of gestation. life limit hafta 24 weeks of gestation). Prenatal diagnosis allows couples with life-compatible anomalies to be found at a time when their life limit has not yet reached, and the freedom to continue pregnancy. Because of their various beliefs, there are also couples who are determined to bring the baby into the world despite these anomalies, and the law has left them to this decision. chromosome). This extra chromosome, that is, DNA information, causes overexpression of various genes at the cellular level, not twice, but twice, resulting in abnormalities in the production of various substances. When abnormalities at this cellular level are reflected in your baby's body, we come across a collection of symptoms called syndromes. Each of the trisomy syndromes has their own characteristics, but they have common features. The tube is the tube structure that makes up the baby's brain and spinal cord. In a child who develops normally immediately after fertilization, this tube closes properly on both sides until the fourth week. If the tube is not properly closed, a Neural Tube Defect may occur. Spina Bifida and Anencephaly are important problems in the development of the spine and brain, two of which are referred to as Neural Tube Disorders. Problems occur during the early stages of pregnancy and during the first 3 to 4 weeks of pregnancy and usually the woman does not even know that she is pregnant.